2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-132592D
    FAM labled Suvodirsen sodium 98%
    FAM labled Suvodirsen sodiumis a FAM labled Suvodirsen sodium.
    FAM labled Suvodirsen sodium
  • HY-132592E
    Cy3 labled Suvodirsen sodium 98%
    Cy3 labled Suvodirsen sodium is a Cy3 labled Suvodirsen sodium.
    Cy3 labled Suvodirsen sodium
  • HY-132604C
    Fazirsiran sodium scrambled negative control 98%
    Fazirsiran sodium scrambled negative control is the sequence scrambled negative control of Fazirsiran sodium.
    Fazirsiran sodium scrambled negative control
  • HY-132604D
    FAM labled Fazirsiran sodium 98%
    FAM labled Fazirsiran sodiumis a FAM labled Fazirsiran sodium.
    FAM labled Fazirsiran sodium
  • HY-132604E
    Cy3 labled Fazirsiran sodium 98%
    Cy3 labled Fazirsiran sodium is a Cy3 labled Fazirsiran sodium.
    Cy3 labled Fazirsiran sodium
  • HY-132606D
    FAM labled Nedosiran sodium 98%
    FAM labled Nedosiran sodiumis a FAM labled Nedosiran sodium.
    FAM labled Nedosiran sodium
  • HY-132606E
    Cy3 labled Nedosiran sodium 98%
    Cy3 labled Nedosiran sodium is a Cy3 labled Nedosiran sodium.
    Cy3 labled Nedosiran sodium
  • HY-132610E
    Givosiran sodium scrambled negative control 98%
    Givosiran sodium scrambled negative control is the sequence scrambled negative control of Givosiran sodium.
    Givosiran sodium scrambled negative control
  • HY-132610H
    FAM labled Givosiran sodium 98%
    FAM labled Givosiran sodiumis a FAM labled Givosiran sodium.
    FAM labled Givosiran sodium
  • HY-132610I
    Cy3 labled Givosiran sodium 98%
    Cy3 labled Givosiran sodium is a Cy3 labled Givosiran sodium.
    Cy3 labled Givosiran sodium
  • HY-132613A
    Lumasiran sodium scrambled negative control 98%
    Lumasiran sodium scrambled negative control is the sequence scrambled negative control of Lumasiran sodium.
    Lumasiran sodium scrambled negative control
  • HY-132613B
    FAM labled Lumasiran sodium 98%
    FAM labled Lumasiran sodiumis a FAM labled Lumasiran sodium.
    FAM labled Lumasiran sodium
  • HY-132613C
    Cy3 labled Lumasiran sodium 98%
    Cy3 labled Lumasiran sodium is a Cy3 labled Lumasiran sodium.
    Cy3 labled Lumasiran sodium
  • HY-133007R
    Algestone acetophenide (Standard) 24356-94-3
    Algestone acetophenide (Standard) is the analytical standard of Algestone acetophenide. This product is intended for research and analytical applications. Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive.
    Algestone acetophenide (Standard)
  • HY-133022R
    trans-2-Undecenoic acid (Standard) 15790-94-0
    trans-2-Undecenoic acid (Standard) is the analytical standard of trans-2-Undecenoic acid. This product is intended for research and analytical applications. trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O[1].
    trans-2-Undecenoic acid (Standard)
  • HY-133068A
    (E)-5-Hydroxyferulic acid 110642-42-7 98%
    (E)-5-Hydroxyferulic acid is the E-isomer of 5-Hydroxyferulic acid (HY-133068). 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat.
    (E)-5-Hydroxyferulic acid
  • HY-133178R
    Urolithin D (Standard) 131086-98-1
    Urolithin D (Standard) (3,4,8,9-Tetrahydroxy urolithin (Standard)) is the analytical standard of Urolithin D (HY-133178). This product is intended for research and analytical applications. Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 μM. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases.
    Urolithin D (Standard)
  • HY-133588R
    4-Formylaminoantipyrine (Standard) 1672-58-8 98%
    4-Formylaminoantipyrine (Standard) is the analytical standard of 4-Formylaminoantipyrine. This product is intended for research and analytical applications. 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo.
    4-Formylaminoantipyrine (Standard)
  • HY-133683R
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard) 503610-29-5
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard) is the analytical standard of N-(3-Oxotetradecanoyl)-DL-homoserine lactone. This product is intended for research and analytical applications. N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule[1][2].
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard)
  • HY-133724R
    Vardenafil N-oxide (Standard) 448184-48-3
    Vardenafil N-oxide (Standard) is the analytical standard of Vardenafil N-oxide. This product is intended for research and analytical applications. Vardenafil N-oxide is a N-Oxide impurity of Vardenafil (HY-B0442).
    Vardenafil N-oxide (Standard)
Cat. No. Product Name / Synonyms Application Reactivity